学术报告：Labeling and Visualizing Glycans with Specificity and Versatility
报告题目：Labeling and Visualizing Glycans with Specificity and Versatility
报 告 人：陈兴（北京大学特聘研究员）
报告时间：2014年9月18日（星期四）上午10:30
报告地点：嘉定园区学术活动中心多功能厅
报告简介：
Glycosylation plays a key role in mediating molecular recognition, development, and cell signaling. Our research group works on developing chemical tools to label, visualize, and manipulate glycosylation. Here, we present the development of a liposome-based strategy for cell-selective metabolic labeling of glycans and a FRET-based method for protein-specific imaging of cell-surface glycans. We also Furthermore, we design and synthesize bifunctional unnatural sugars that introduce simultaneously two functional groups into cellular glycans. The bifunctional sugar analogs are valuable tools for profiling glycan-protein interactions. Finally, we are interested in developing new imaging modalities for glycan visualization. A recently developed bioorthogoal Raman imaging technique will be discussed.
报告人简历：
Resume_XC_new_2014.pdf
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